Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add filters








Year range
1.
Arq. bras. cardiol ; 65(3): 255-258, Set. 1995. ilus, tab
Article in Portuguese | LILACS | ID: lil-319341

ABSTRACT

PURPOSE--To assess the hemodynamic effects of milrinone in a 48h intravenous infusion in patients with severe congestive heart failure (CHF) (NYHA class III or IV). METHODS--Forty patients with CHF were sequentially evaluated. Right heart catheterization was performed in order to measure, before and after administration of milrinone, several hemodynamic parameters (cardiac index, pulmonary wedge pressure, systemic and pulmonary vascular resistance). RESULTS--There was a significant improvement in hemodynamic parameters (cardiac index, cardiac output), and a decrease in systemic vascular resistance and pulmonary vascular resistance. Serious side effects were not observed in these patients. CONCLUSION--These findings indicate that milrinone is effective in the treatment of deteriorating phases of CHF and suggest that milrinone should be used in these select patients.


Objetivo - Verificar os efeitos hemodinâmicos a curto prazo, da infusão intravenosa de milrinona em portadores de insuficiência cardíaca congestiva (ICC), grau funcional (GF) III e IV da NYHA. Métodos - Foram estudados, prospectivamente, 40 pacientes, com ICC de diversas etiologias, GF III e IV da NYHA e, através do cateter de Swan-Ganz, analisados vários parâmetros hemodinômicos como, índice cardíaco (IC), pressão capilar pulmonar, resistência vascular sistêmica (RVS) e pulmonar (RVP), antes e após a infusão de milrinona. Analisaram-se, também, os efeitos clínicos e possíveis efeitos colaterais da droga. Resultados - Significante melhora clínica e hemodinâmica, avaliada pelo cateter de Swan-Ganz. Aumento significante do IC, com queda expressiva da RVS, RVP, sem causar hipotensão e ou taquifilaxia. Não houve aparecimento de efeitos colaterais graves que justificassem a interrupção do tratamento. Conclusão - Este tipo de fármaco inodilatador pode e deve ser usado em fases agudas da descompensação cardíaca nestes pacientes


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Pyridones , Cardiotonic Agents/administration & dosage , Heart Failure/drug therapy , Prospective Studies , Milrinone , Acute Disease , Hemodynamics/drug effects , Infusions, Intravenous , Heart Failure/classification
2.
Arq. bras. cardiol ; 58(6): 453-455, jun. 1992. tab
Article in Portuguese | LILACS | ID: lil-123253

ABSTRACT

Objetivo - Verificar o beneficio a curto e a longo prazo de pacientes submetidos a troca valvar aórtica isolada e a troca valvar associada a revascularizaçäo do miocárdio (RM), avaliar a incidência das complicaçöes pós-operatórias (CPO), mortalidade hospitalar (MH) e mortalidade tardia (MT). Métodos - Vinte pacientes foram tratados cirurgicamente entre janeiro de 1985 e dezembro de 1989, 75% (15 pacientes) do sexo masculino e 25% (5 pacientes) do sexo feminino, variando as idades entre 70 e 86 (média = 74,8) anos e com gradiente valvar aórtico entre 78 e 180 mmHg (média = 97 mmHg), com diagnóstico pré-operatório de estenose aórtica (EA) isolada ou EA associada com insuficiência coronariana (ICo). Estavam em grau funcional (NYHA) I - O paciente; II - 3 pacientes (15%); III - 14 pacientes (70%) e IV - 3 pacientes (15%). Resultados - As CPO mais freqüentes foram: intubaçäo prolongada em 7 pacientes (35%), sangramento em 4 pacientes (20%), insuficiência renal aguda em 3 pacientes e arritmia ventricular em 3 pacientes (15%). A MH foi de 10% (2 paciente), todos com cirurgia de troca valvar associada a RM. A MT foi de 5% (1 paciente). Até dezembro de 1989, 11 pacientes (64%) encontravam-se em grau funcional I, 3 pacientes (18%) em II, 3 pacientes (18%) em III e nenhum em IV. Conclusäo - A idade avançada näo é uma contra-indicaçäo de cirurgia para os pacientes com estnose aórtica isolada ou associada com ICo. Em relaçäo ao pré-operatório houve uma significativa melhora do grau funcional (NYHA) dos pacientes sobreviventes


Purpose - To assess the short and long-term benefits of patients who were submitted to isolated aortic valve replacement or valve replacement (VR) concomitant myocardial revascularization (MR); to evaluate the incidence of postoperative complications, hospital mortality and late mortality. Methods -- From January 1985, through December 1989, 20 consecutive patients underwent surgical intervention, 15 male (75%) and 5 female (25%), the mean age was 74.8% (ranging from 70 to 86 years old ), and the aortic valve gradient ranged between 78 and 180 mmHg (mean = 97 mmHg). They presented preoperative diagnosis to have either isolated aortic stenosis (AS) or As and coronary artery disease (CAD). No patient was in NYHA functional class I; 3 patients (15%) were in class II, 14 (70% ) in class III and 3 (15%), in class IV. Results - The most frequent post-operative complications found were: extended intubation in 7 patients (35%), bleeding in 4 (20%), acute renal failure in 3 (15% ) and ventricular arrhythmia in 3 (15%). Hospital mortality ocurred in 2 patients (10%) who had been submitted to VR and concomitant MR. Late mortality occurred in 1 patient (5%). Through Dezember 1989,11 patients (64%) were in functional classe I (NYHA), 3 (18%) in class II, 3 (18%) in classe III and none in class IV. Conclusion - We concluded that the surgical treatment is indicate to elderly patients with isolated AS os with AS and concomitant CAD. There was a significant post-operative improvement of the functional class (NYHA) to the surviving patients


Subject(s)
Humans , Male , Female , Aged , Aortic Valve Stenosis/surgery , Aortic Valve/surgery , Aged, 80 and over , Heart Valve Prosthesis , Retrospective Studies , Postoperative Complications , Prognosis , Myocardial Revascularization
SELECTION OF CITATIONS
SEARCH DETAIL